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Two cases of urothelial cancer responsive to high-dose-intensity methotrexate vinblastine doxorubicin and cisplatin (M-VAC) therapy |
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| Authors: | Fukuda Hisami Mitsumori Kenji Minagawa Shingo Kumazawa Teruaki Tadachi Kazuteru Iinuma Masahiro Satoh Shigeru Satoh Kazunari Habuchi Tomonori Kato Tetsuro |
| Affiliation: | Department of Urology, Akita University School of Medicine. |
| Abstract: | We report two cases of metastatic urothelial cancer treated with high-dose-intensity (HD) methotrexate vinblastine, doxorubicin and cisplatin (MVAC). After HD-MVAC, the size of primary and lymph node tumors decreased by 57-67% as compared with the standard M-VAC therapy. By shortening the dose interval, HD-MVAC may increase the anti-tumor effect without increasing side effects. |
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