Practical considerations for the dosing and adjustment of continuous renal replacement therapy in the intensive care unit |
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| Authors: | Samuel M. Galvagno Jr. Caron M. Hong Matthew E. Lissauer Andrew K. Baker Sarah B. Murthi Daniel L. Herr Deborah M. Stein |
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| Affiliation: | 1. Division of Critical Care Medicine, Department of Anesthesiology, University of Maryland Medical School, Baltimore, MD;2. Division of Trauma Anesthesiology, Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland Medical School, Baltimore, MD;3. Division of Critical Care Medicine, Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD;4. Division of Acute Care Surgery, Department of Surgery, University of Maryland Medical School, Baltimore, MD;5. Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland Medical School, Baltimore, MD;6. ST7 in Anaesthesia and Intensive Care Medicine, Dorset County Hospital, Dorchester, UK;g Departments of Medicine and Surgery, University of Maryland School of Medicine, Baltimore, MD;h Department of Surgery, Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland Medical School, Baltimore, MD |
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| Abstract: | ![]()
Familiarity with the initiation, dosing, adjustment, and termination of continuous renal replacement therapy (CRRT) is a core skill for contemporary intensivists. Guidelines for how to administer CRRT in the intensive care unit are not well documented. The purpose of this review is to discuss the modalities, terminology, and components of CRRT, with an emphasis on the practical aspects of dosing, adjustments, and termination. Management of electrolyte and acid-base derangements commonly encountered with acute renal failure is emphasized. Knowledge regarding the practical aspects of managing CRRT in the intensive care unit is a prerequisite for achieving desired physiological end points. |
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| Keywords: | Dosing Continuous renal replacement therapy Intensive care unit |
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