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Validation and workflow optimization of human epidermal growth factor receptor 2 testing using INFORM HER2 dual-color in situ hybridization
Authors:Sung-Jig Lim  Alegria Cantillep  Philip M. Carpenter
Affiliation:1. Department of Pathology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul 134-727, South Korea;2. Department of Pathology and Laboratory Medicine, University of California, Irvine, Orange 92868, CA
Abstract:
Keywords:HER2, human epidermal growth factor receptor 2   IHC, immunohistochemistry   ISH, in situ hybridization   FFPE, formalin-fixed, paraffin-embedded   GOLDFISH, nanogold with enhancement in situ hybridization   FISH, fluorescence in situ hybridization   CISH, chromogenic in situ hybridization   SISH, silver-enhanced in situ hybridization   Dual ISH, INFORM HER2 Dual-color in situ hybridization   FDA, United States Food and Drug Administration   ER, estrogen receptor   PR, progesterone receptor   DNP, dinitrophenyl   Chr17, chromosome 17 centromere   TAT, turnaround time
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