T2图和扩散加权成像对膝关节软骨早期损伤的临床应用研究

目的：研究T2图（T2-mapping）扩散加权成像（DWI）在早期软骨损伤中的临床诊断价值。方法：30例正常志愿者和42例早期骨软骨损伤患者分别行B图和DWI，所得图像经工作站后处理测量软骨的T2值和ADC值。统计学比较正常组和早期软骨损伤组软骨T2值和ADC值有无差异。结果：正常组软骨的平均T2值和ADC值分别为（39．54±4．02）ms和（1．44±0．17）×10^-3mm^2／s；早期软骨损伤组为（51．58±4．15）ms和（1．78±0．35）×10^-3mm^2／s；其T2值和ADC值有显著性差异（P〈0．01）。结论：早期软骨损伤时软骨的T2值和ADC值均有明显升高，T2图和扩散加权成像对诊断早期软骨损伤具有很高的临床应用价值。

The clinical applied study of knee cartilage early injure by T_2-mapping and DWI

Objective：To study the clinical diagnostic value of T2-mapping and DWI in early cartilage injury.Methods：72 subjects ineluding healthy group （n = 30）, early cartilage injure group （n = 42） underwent MR scan with T2-mapping and DWI. Through post-processed in workstation, T2 value and ADC value of cartilage were measured and the differences were statistically analyzed between the two groups. Results：Tile mean T2 and ADC value of cartilage were（39.54 ± 4.02） ms and （1.44 ±0.17）× 10^-3 mm^2/s, in healthy group, respectively. （51.58 ± 4.15） ms and （1.78 ± 0.35） × 10^-3 mm^2/s in early cartilage injure group, respectively, which were significant difference between healthy and early cartilage injury group （ P 〈 0.01）. Conclusion：T2 value and ADC value of cartilage in early artilage injury group are obviously increased, MR T2-mapping and DWI have highly clinical value in diagnosis of early articular cartilage injury.