| P物质和降钙素基因相关肽在大鼠垂体前叶神经纤维内的共存 |
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| 引用本文： | 董玉书,刘惠玲,张萍,鞠躬. P物质和降钙素基因相关肽在大鼠垂体前叶神经纤维内的共存[J]. 神经解剖学杂志, 2005, 21(3): 238-240 |
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| 作者姓名： | 董玉书 刘惠玲 张萍 鞠躬 |
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| 作者单位： | 第四军医大学,全军神经科学研究所,西安,710032;第四军医大学,全军神经科学研究所,西安,710032;第四军医大学,全军神经科学研究所,西安,710032;第四军医大学,全军神经科学研究所,西安,710032 |
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| 摘 要： | 为观察P物质(SP)和降钙素基因相关肽(CGRP)在大鼠垂体前叶神经纤维内的共存,用种属特异性抗体(兔抗-SP多克隆抗体和小鼠抗-CGRP单克隆抗体)进行免疫荧光双标记,激光共聚焦扫描显微镜观察进行研究。结果显示:所有的CGRP免疫阳性神经纤维都是SP免疫阳性,同时所有的SP免疫阳性神经纤维也都是CGRP免疫阳性;CGRP免疫阳性神经纤维的分布和形态与SP免疫阳性神经纤维相一致。结论:P物质和降钙素基因相关肽在大鼠垂体前叶神经纤维内完全共存。
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| 关 键 词： | P物质 降钙素基因相关肽 递质共存 垂体前叶 大鼠 |
| 修稿时间： | 2004-10-28 |
CO-EXISTENCE OF SUBSTANCE P AND CALCITONIN GENE-RELATED PEPTIDE IN RAT ANTERIOR PITUITARY NERVE FIBERS |
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| Dong Yushu,LIU Huiling,Zhang Ping,JU Gong. CO-EXISTENCE OF SUBSTANCE P AND CALCITONIN GENE-RELATED PEPTIDE IN RAT ANTERIOR PITUITARY NERVE FIBERS[J]. Chinese Journal of Neuroanatomy, 2005, 21(3): 238-240 |
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| Authors: | Dong Yushu LIU Huiling Zhang Ping JU Gong |
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| Abstract: | To investigate the co-existence of SP and CGRP in rat anterior pituitary nerve fibers, double-immunofluorescence and laser scanning confocal microscopy were used in this study. All of the CGRP-like immunoreactive nerve fibers examined were also SP-like immu-noreactive and vice versa. The distribution and morphology of CGRP- and SP-like immunoreactive nerve fibers were the same. The results demonstrated that SP and CGRP completely co-exist in the nerve fibers of the rat anterior pituitary. |
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| Keywords: | Substance P calcitonin gene-related peptide transmitters co-existence anterior pituitary rat |
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