Nutrition Support and Infections Associated With Hepatic Resection and Liver Transplantation in Patients With Chronic Liver Disease |
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Authors: | Toshiro Masuda MD PhD Ken Shirabe MD PhD Shohei Yoshiya MD Rumi Matono MD Kazutoyo Morita MD PhD Naotaka Hashimoto MD PhD Toru Ikegami MD PhD Tomoharu Yoshizumi MD PhD Hideo Baba MD PhD Yoshihiko Maehara MD PhD |
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Affiliation: | 1. Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;2. Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan |
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Abstract: | Malnutrition is common in liver cirrhotic patients who will undergo liver resection or liver transplantation. A precise evaluation of their nutrition status is thus difficult because of the presence of ascites and the edema caused by their impaired protein synthesis. Both perioperative enteral and parenteral nutrition have benefits in reducing the morbidity and mortality of liver surgery, and in general, oral nutrition supplements are recommended. Branched‐chain amino acids (BCAAs) promote protein and glycogen synthesis and regulate immune system function. Synbiotics, a combination of pro‐ and prebiotics, is reported to enhance immune responses. Oral nutrition support with BCAAs, synbiotics, and an immune‐enhancing diet have a beneficial effect on preventing the perioperative infections associated with hepatic resection or liver transplantation. |
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Keywords: | nutrition infection bacteremia liver cirrhosis liver surgery hepatic resection liver transplantation branched‐chain amino acids synbiotics |
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