带状疱疹初期疗法与神经痛疗效的相关性研究

目的 探讨带状疱疹初期治疗方法与神经痛疗效的关系.方法 将120例带状疱疹患者随机分为3组,A组给予泛昔洛韦,B组给予泛昔洛韦联合复方甘草酸苷,C组给予阿昔洛韦联合复方甘草酸苷,疗程均为7 d,随访1个月.结果 疼痛缓解和消失时间B组最短,与A、C两组比较差异均有统计学意义(P＜0.05),A、C两组相近(P＞0.05).A、B、C三组痊愈率1周时分别为40.0%、65.0%和37.5%,2周时分别为62.5%、90.0%和70.0%,4周时分别为90.0%、100.0%和97.5%,B组与A、C组差异有统计学意义(P＜0.05).结论 本研究中,泛昔洛韦联合复方甘草酸苷治疗初期带状疱疹疼痛疗效最好.

Correlational study of initial treatment for herpes zoster and neuralgia

Objective To investigate the relations of initial treatment for herpes zoster and neuralgia effect.Methods 120 patients with herpes zoster were randomly divided into three groups. Group A were given famciclovir,group B were combined with famciclovir and compound glycyrrhizin, group C were combined with acyclovir and compound glycyrrhizin, all the cases were treated for 7 days, and followed up for 1 month. Results The time of pain relief and disappearance in group B were the shortest among three groups, there were statistical differences compared to group A and C ( P ＜0.05), and there was no difference between group A and C ( P ＞0.05). The cure rates after 1 week treatment in group A, B and C were 40.0%, 65.0% and 37.5% respectively; after 2 weeks, the rates were 62.5%, 90.0% and 70.0%; after 4 weeks, the rates were 90.0%, 100.0% and 97.5%, and group B was statistical differences compared with group A and C( P ＜ 0.05). Conclusions The effect of famciclovir combined compound glycyrrhizinis is the best for treating herpes zoster in this study.