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Effect of aloe vera mouthwash on dental plaque and gingivitis indices in children: A randomized controlled clinical trial
Institution:1. Department of Pediatric Dentistry, Faculty of Dental Medicine, Damascus University, Damascus, Syria;2. Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Damascus University, Damascus, Syria;3. Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dental Medicine, Damascus University, Damascus, Syria;1. Department of Pediatric Dentistry, Faculty of Dentistry, Damascus University, Al-Mazzeh St. Damascus, PO Box 30621, Syria;2. Department of Endodontic, Faculty of Dentistry, Damascus University, Al-Mazzeh St. Damascus, PO Box 30621, Syria;3. Department of Oral Medicine, Faculty of Dentistry, Damascus University, Al-Mazzeh St. Damascus, PO Box 30621, Syria;1. Department of Pediatric & Preventive Dentistry, JSS Dental College & Hospital, JSS Academy of Higher Education & Research, Mysuru, India;2. Department of Oral Pathology & Microbiology, JSS Dental College & Hospital, JSS Academy of Higher Education & Research, Mysuru, India;1. Department of Pediatric Dentistry, Rutgers School of Dental Medicine, USA;2. Rutgers School of Dental Medicine, USA;3. Department of Oral Biology, Rutgers School of Dental Medicine, USA;1. Section of Pediatric Dentistry, Department of Oral Growth and Development, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0193, Japan;2. Section of Functional Structure, Department of Morphological Biology, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0193, Japan;3. Kato Dental Office for Children, Sawara-ku, Fukuoka, Japan;1. Division of Pediatric Dentistry, Department of Oral Health and Development Sciences, Tohoku University Graduate School of Dentistry, Sendai, 980-8575, Japan;2. Section of Pediatric Dentistry, Division of Oral Health, Growth, and Development, Kyushu University Faculty of Dental Science, Fukuoka, 812-8582, Japan;3. Department of Pediatric Dentistry, Tokushima University of Graduate School, Tokushima, 770-8504, Japan;4. Department of Oral Anatomy II, Iwate Medical Collage School of Dentistry, Morioka, 020-8505, Japan
Abstract:BackgroundThere is a tendency nowadays to encourage the use of natural substances in dentistry. Aloe vera is one of these substances, which has recently gained great importance in clinical research.ObjectivesTo evaluate the effectiveness of Aloe vera mouthwash in improving plaque, gingival and gingival bleeding indices in children.Materials and methodsThe study sample consisted of (17) children age: (8) to (12) years]. The crossover design was applied, which means that the three types of mouthwashes (experimental “Aloe vera”, positive control “chlorhexidine”, and negative control “placebo”) would be used for all participants, with a washout period of (12) days. A special plaque guard was fabricated to facilitate localized plaque accumulation for (3) days. After that period, the mouthwashes were applied for (5) days. Plaque, gingival and gingival bleeding indices were studied before plaque accumulation (T0), after plaque accumulation (T1), and after applying the mouthwashes (T2). The values of plaque index (PI), gingival index (GI) and gingival bleeding index (GBI) were measured at each studied time point (T0, T1, and T2). Then, the differences between the values at the beginning of the use of each type of the mouthwashes and at the end of the period of there use were compared.ResultsThe results showed the efficacy of Aloe vera mouthwash in improving plaque, gingival and gingival bleeding indices, which was similar to chlorhexidine mouthwash effectiveness when both compared to the placebo mouthwash.ConclusionsThe use of Aloe vera mouthwash is effective in improving oral health and preventing gingivitis.
Keywords:Aloe vera mouthwash  Chlorhexidine mouthwash  Dental plaque index  Gingival index  Gingival bleeding index
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