| 赖诺普利对高血压患者心钠素及左室肥厚的影响 |
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| 引用本文： | 吴云,赵兴胜,贺文帅,贺利平. 赖诺普利对高血压患者心钠素及左室肥厚的影响[J]. 内蒙古医学杂志, 2009, 41(5): 521-524 |
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| 作者姓名： | 吴云 赵兴胜 贺文帅 贺利平 |
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| 作者单位： | 内蒙古自治区医院心内科,内蒙古,呼和浩特,010017;内蒙古自治区医院心内科,内蒙古,呼和浩特,010017;内蒙古自治区医院心内科,内蒙古,呼和浩特,010017;内蒙古自治区医院心内科,内蒙古,呼和浩特,010017 |
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| 摘 要： | 目的：探讨高血压（EH）患者心钠素（ANP））、空腹血清胰岛素（FINS）与左室肥厚（LVH）的关系以及赖诺普利对其的影响。方法：入选病例为符合2005年《中国高血压防治指南》标准的1级、2级EH伴LVH的患者60例,随机分为赖诺普利组30例,卡托普利组30例。检测口服赖诺普利或卡托普利前后ANP、FINS的含量;采用彩色多普勒超声检测LVH。样本数据分析采用t检验或多元线性回归。结果：赖诺普利较卡托普利降低ANP、FINS及改善LVH效果更显著（P〈0.05）;ANP、FINS与LVH无相关性。结论：赖诺普利可降低ANP、FINS。
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| 关 键 词： | 高血压 左室肥厚 赖诺普利 心钠素 空腹血清胰岛素 |
Effect of Lisinopril on Atrial Natriuretic Peptide and Left Ventricular Hypertrophy In Essential Hypertension |
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| WU Yun,ZHAO Xing-sheng,HE Wen-shuai,HE Li-ping. Effect of Lisinopril on Atrial Natriuretic Peptide and Left Ventricular Hypertrophy In Essential Hypertension[J]. Inner Mongolia Medical Journal, 2009, 41(5): 521-524 |
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| Authors: | WU Yun ZHAO Xing-sheng HE Wen-shuai HE Li-ping |
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| Affiliation: | Department of Cardiology;Inner Mongolia Hospital;Huhhot 010017 China |
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| Abstract: | Objective:To investigate the relationshop among atrial natriuretic peptide(ANP),fasting serum lisulin(FINS) and left ventricular hypertrophy(LVH) in essential hypertension(EH) and the effect of lisinopril on ANP,FINS and LVH.Methods:60 cases of EH in grade 1 and grade 2 with LVH were enrolled and dividedly into two groups:group with lisinopril(n=30) and group with captopril(n=30).The levels of ANP and FINS before and after administrations were detected,and the severity of LVH was measured by color Dopper ul... |
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| Keywords: | Hypertension Left ventricular hypertrophy （LVH） Lisinopril Atrial natriuretic peptide （ANP） Fasting serum lisulin（FINS） |
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