| 血浆BNP检测在慢性心衰诊断及治疗中的应用 |
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| 引用本文： | 葛咏梅,张立江. 血浆BNP检测在慢性心衰诊断及治疗中的应用[J]. 中国实验诊断学, 2009, 13(11): 1572-1573 |
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| 作者姓名： | 葛咏梅 张立江 |
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| 作者单位： | 1. 吉林省人民医院,检验科,吉林,长春,130021
2. 长春市肝胆医院 |
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| 摘 要： | 目的探讨血浆BNP（B型利钠肽）水平在心力衰竭（CHF）诊断及治疗中的应用。方法采用化学发光法测定53例已确诊心衰患者和4JD例健康人血浆BNP的含量。结果CHF患者BNP含量的中位数和四分位数间距为（426．7±502．3）pg／ml，对照组BNP含量相应为（16．2±20．7）pg／ml，两者有显著差异（Z=14．12，P〈0．001）。BNP水平随心功能NYHA分类级别增高而升高，各级间有显著差异（X^2=31．14，P〈0．001）。结论检测BNP可为临床诊断CHF及治疗提供依据。
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| 关 键 词： | BNP 心力衰竭 诊断与治疗 |
To investigate the value of level of plasma BNP in diagnosis and treatment of congestive heart failure |
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| GE Yong-mei,ZHANG Li-jiang. To investigate the value of level of plasma BNP in diagnosis and treatment of congestive heart failure[J]. Chinese Journal of Laboratory Diagnosis, 2009, 13(11): 1572-1573 |
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| Authors: | GE Yong-mei ZHANG Li-jiang |
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| Affiliation: | GE Yong-mei, ZHANG Li-jiang. ( The Peoele＇ s Hospital of Jilin Province, Department of Clinical Laboratory, Changchun 130021, China ) |
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| Abstract: | Objective To investigate the value of level of plasma BNP in diagnosisand treatment of congestive heart failure. Methods plasma blood BNP was measured in CHF group （ n = 53） and control group （ n = 46） with assay Results The levels of BNP＇ s median ± interquartile range were （426.7 ± 502.3） pg/ml and （ 16.2 ± 20.7） pg/ml in the CHF group and the control group respectively, there was significant difference between the two groups （Z = 14.12, P 〈 0. 001 ）. Blood BNP concentrations of CHF group increased with the severity of CHF. Conclusion BNP is of great value for the clinical diagnosis and treatment of congestive heart failure. |
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| Keywords: | BNP |
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