Modification of hemorheologic parameters by beta-receptor blockers with special reference to propranolol and talinolol |
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Authors: | H R B?hme A Neupert W Fischer |
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Affiliation: | Institut für Klinische Pharmakologie, Bereich Medizin Karl-Marx-Universit?t Leipzig. |
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Abstract: | There are no systematic and complex investigations regarding the hemorheologic action of the betablockers propranolol and talinolol. The results on the other ones are contradictory. On the basis of a critical survey of the literature, in-vitro-experiments and studies in animals (rats) and humans may conclude that there are no remarkable deteriorations of rheological parameters in the therapeutic dose range. This is valid for diseases only where the haemodynamic regulation doesn't prevail. |
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