| An Overview on the Progress of Chemical Constituents and Bioactivities of Plants in Urticaceae during 2000－2010 |
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| 作者姓名： | WANG Jian YANG Hong-xing TENG Yong-zhen YUAN Pei TIAN Rui LIAO Chun-bi |
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| 作者单位： | College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China;Department of Anesthesiology, Daping Hospital, the Third Military Medical University, Chongqing 400042, China;School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100193, China;Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China;Institute of Life Sciences, Chongqing Medical University, Chongqing 400017, China;Experimental Teaching Administration Center, Chongqing Medical University, Chongqing 400016, China |
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| 摘 要： | Urticaceae includes about 1300 species in 47 genera which largely spread in wet tropical regions, and 341 species in 25 genera are in China. Some species are used in Chinese folk medicine. So far, studies on chemistry and pharmacology of Urticaceous plants are mainly focused on nettle of Urtica L. In this review, the chemical researches on 35 new compounds and related pharmacological effects of the plants in Urticaceae reported during 2000－2010 are described. The 35 new compounds belong to the classes of lignan, secolignan, norlignan, flavonoid, alkaloid, sesquiterpenoid, triterpenoid, sterol, and sphingolipid. The main bioactivities include cytotoxic, antitumor, antimicrobial, antifungal, anti-BPH, anti-HIV, antidiabetic, hypolipidemic, 5α-reductase inhibitory, hair regrowth promotion, and anti-oxidative activities.
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| 收稿时间： | 7/2/2010 12:00:00 AM |
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