| 吸入麻醉药对冠脉搭桥术心肌保护作用的Meta分析 |
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| 引用本文： | 张国荣,张晋东,杨晓明,陈延英,杨改生,叶博,卓九五. 吸入麻醉药对冠脉搭桥术心肌保护作用的Meta分析[J]. 临床麻醉学杂志, 2009, 25(5) |
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| 作者姓名： | 张国荣 张晋东 杨晓明 陈延英 杨改生 叶博 卓九五 |
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| 作者单位： | 解放军空军总医院麻醉科,北京市,100142;解放军空军总医院麻醉科,北京市,100142;解放军空军总医院麻醉科,北京市,100142;解放军空军总医院麻醉科,北京市,100142;解放军空军总医院麻醉科,北京市,100142;解放军空军总医院麻醉科,北京市,100142;解放军空军总医院麻醉科,北京市,100142 |
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| 摘 要： | 目的 评价吸入麻醉药对冠状动脉搭桥术(CABG)心肌缺血-再灌注损伤的保护作用.方法 检索Medline和中国期刊全文数据库,收集各研究中的心脏指数、使用正性肌力药的例数和术后24 h内心肌肌钙蛋白I(cTnI)的最高数值.计数资料采用优势比(OR)和95%可信区间(CI)表示.计量资料用加权平均差(WMD)和95%可信区间表示,统计分析用Revman 4.2.10软件完成.结果 符合标准的文献共23篇,1398例患者.分析显示,吸入麻醉约都能使CABG患者术后的心脏指数增加[WMD=0.41;95%CI(0.17,0.64)],使cTnI明显降低[WMD=-1.61;95%CI(-2.25,-0.96)],需用正性肌力药的患者数减少[OR=0.45;95%CI(0.35,0.58)].结论 七氟醚等吸入麻醉药用于CABG具有明显的心肌保护作用.
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| 关 键 词： | 吸入麻醉药 冠状动脉搭桥术 肌钙蛋白I 心肌保护 Meta分析 |
Effects of inhalation anesthetics on myocardial protection in coronary artery bypass grafting:a meta-analysis |
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| ZHANG Guo-rong,ZHANG Jin-dong,YANG Xiao-ming,et al.. Effects of inhalation anesthetics on myocardial protection in coronary artery bypass grafting:a meta-analysis[J]. The Journal of Clinical Anesthesiology, 2009, 25(5) |
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| Authors: | ZHANG Guo-rong ZHANG Jin-dong YANG Xiao-ming et al. |
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| Affiliation: | ZHANG Guo-rong,ZHANG Jin-dong,YANG Xiao-ming,et al.Department of Anesthesiology,General Hospital of Air Force,Beijing 100142,China |
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| Abstract: | Objective To study the effect of inhalation anaesthetics on myocardial protection during coronary artery bypass grafting(CABG).Methods Data were obtained from searches of Medline and CNKI as well as references listed.It was undertook that only randomized controlled trials(RCTs)evaluating inhalaton anesthetics and intravenous anesthetic drugs or inhalation anesthetics preconditioning during CABG were included.Data were abstracted on cardiac index,inotropic support,and the peak value of troponin I(cTnI)during... |
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| Keywords: | Inhalation anesthetics Coronary artery bypass grafting Troponin I Myocardial protection Meta-analysis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
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