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| 局部振动对家兔脑组织去甲肾上腺素和多巴胺影响的实验研究 | |
| 引用本文： | 苏大禹,马海燕,杜少奎,张春之. 局部振动对家兔脑组织去甲肾上腺素和多巴胺影响的实验研究[J]. 工业卫生与职业病, 2009, 0(1) |
| 作者姓名： | 苏大禹 马海燕 杜少奎 张春之 |
| 作者单位： | 即墨市疾病控制中心;青岛市城阳区疾病控制中心;济宁医学院职业卫生与环境医学研究所; |
| 摘 要： | 目的探讨振动对脑组织去甲肾上腺素和多巴胺的影响及其与振动性神经病发病机制的关系。方法将家兔按不同强度分组进行接振45 d后,测定对照组和实验组家兔脑组织中的去甲肾上腺素(noradrenalin,NE)和多巴胺(dopamine,DA)含量。结果与对照组比较,各实验组NE含量显著降低(P<0.01);实验组DA含量显著降低,其中,中、高剂量组与对照组比较,差异有统计学意义(P<0.01)。结论振动对中枢神经系统产生影响,其可能与振动性神经病的发病机制有关。 |
| 关 键 词： | 局部振动 振动性神经病 去甲肾上腺素 多巴胺 实验研究 |
Study on the Effects of Local Vibration on Noradrenalin and Dopamine in Rabbit Brains |
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| SU Da-yu,MA Hai-yan,DU Shao-kui,ZHANG Chun-zhi. Study on the Effects of Local Vibration on Noradrenalin and Dopamine in Rabbit Brains[J]. Industrial Health and Occupational Diseases, 2009, 0(1) | |
| Authors: | SU Da-yu MA Hai-yan DU Shao-kui ZHANG Chun-zhi |
| Affiliation: | * Center for Disease Control and Prevention;Jimuo 266200 China |
| Abstract: | Objective To study the effects of local vibration on noradrenalin and dopamine of rabbit brain tissues,and its association with vibration-induced neuropathy.Methods Rabbits were randomly divided into 4 groups and exposed to vibration at different levels for 45 days.After the test,the contents of noradrenalin and dopamine in brain tissues were measured in each group.Results Compared with the control group,the concentration of noradrenalin in all exposure groups decreased significantly(P<0.01).Dopamine of hig... |
| Keywords: | Local vibration Vibration-induced neuropathy Noradrenalin Dopamine Experimental study |
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