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Phenotypic Clusters Predict Outcomes in a Longitudinal Interstitial Lung Disease Cohort
Authors:Ayodeji Adegunsoye  Justin M. Oldham  Jonathan H. Chung  Steven M. Montner  Cathryn Lee  Leah J. Witt  Danielle Stahlbaum  Rene S. Bermea  Lena W. Chen  Scully Hsu  Aliya N. Husain  Imre Noth  Rekha Vij  Mary E. Strek  Matthew Churpek
Affiliation:1. Section of Pulmonary & Critical Care, Department of Medicine, University of Chicago, Chicago, IL;2. Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of California at Davis, Davis, CA;3. Department of Radiology, University of Chicago, Chicago, IL;4. Department of Medicine, University of Chicago, Chicago, IL;5. Department of Pathology, University of Chicago, Chicago, IL
Abstract:
Keywords:cluster  interstitial lung disease  mortality  phenotype  pulmonary fibrosis  ANA  antinuclear antibody  ATS  American Thoracic Society  CHP  chronic hypersensitivity pneumonitis  CTD  connective tissue disease  CTD-ILD  connective tissue disease-associated interstitial lung disease  diffusing capacity of the lungs for carbon monoxide  ERS  European Respiratory Society  GAP-ILD  gender, age, physiology-interstitial lung disease  HR  hazard ratio  HRCT  high-resolution CT  ILD  interstitial lung disease  IPAF  interstitial pneumonia with autoimmune features  IPF  idiopathic pulmonary fibrosis  NSIP  nonspecific interstitial pneumonia  PA  pulmonary artery  PAM  partitioning around medoids  PFS  progression-free survival  PFT  pulmonary function test  SLB  surgical lung biopsy  TFS  transplant-free survival
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