男性2型糖尿病患者骨密度的变化

目的 观察男性2型糖尿病患者骨密度的变化。方法 采用双能X线吸收法（DEXA）测定811例男性2型糖尿病患者腰椎正位1～4椎体（L1-4）、左侧髋部股骨颈（Neck）、大转子（Troch）、转子内区（Imer）、髋部总体（Total）和华氏三角（ward’s）的骨密度。结果 （1）男性2型糖尿病患者L1-4骨密度的改变先随年龄增加而逐渐降低，60岁之后又逐渐增高；Neck、Troch、Inter、Total和Ward’s区骨密度随年龄增加而逐渐降低，特别是Ward’s区骨密度下降显著。（2）病程在各年龄段对骨密度无明显影响。（3）超重组骨密度〉正常体重组〉低体重组。结论 病程对男性2型糖尿病患者骨密度无影响，Ward’s区是观察骨密度变化的敏感区域。

Changes of bone mineral density in male patients with type 2 diabetes

Objective To investigate the changes of bone mineral density(BMD) in male patients with type 2 diabetes(T2DM). Methods BMD of L_ 1-4 , neck, Troch, Inter, Total and Ward's region was measured by DXA QDR-4500A in 811 male patients with T2DM. Results BMD of L_ 1-4 ,neck, Troch, Inter, Total and Ward's all decreased with age, especially that of Ward's, but BMD of the L_ 1-4 increased after 60. The courses of diabetes had no effect on BMD in any age group in these male patients. BMD increased with the body mass index (BMI). Conclusions The course of T2DM has no effect on BMD in male patients. Ward's area is a sensitive region for observing the BMD variations.