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TCDD treatment eliminates the long-term reconstitution activity of hematopoietic stem cells.
Authors:Ruriko Sakai  Teruyuki Kajiume  Hiroko Inoue  Rieko Kanno  Masaki Miyazaki  Yuichi Ninomiya  Masamoto Kanno
Affiliation:Department of Immunology, Graduate School of Biomedical Science, Hiroshima University, Minami-ku, Hiroshima 734-8551, Japan.
Abstract:
Keywords:2,3,7,8-tetrachlorodibenzo-p-dioxin   TCDD   hematopoietic stem cells (HSCs)   CD34-KSL (CD34-, c-kit+, Sca-1+, lineage negative) cells   long-term reconstitution activity   aryl hydrocarbon receptor   AhR.
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