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Therapeutic failure of cinacalcet in a renal transplant patient presenting hyperparathyroidism with severe hypercalcaemia
Authors:Boulanger, Henri   Haymann, Jean Philippe   Fouqueray, Bruno   Mansouri, Rafik   Metivier, Fabien   Sarfati, Emile   Glotz, Denis
Affiliation:1 Department of Nephrology andTransplantationSaint-Louis Hospital2 Department of Renal PhysiologyTenon Hospital3 Department of General SurgerySaint-Louis HospitalParisFrance
Abstract:
Sir, In our experience, ~10% of renal allograft recipients developsustained hyperparathyroidism and hypercalcaemia during thefirst year following renal transplantation. Persistent hypercalcaemiausually requires parathyroidectomy, which represents the onlydefinitive treatment currently available. Cinacalcet, a calcimimeticdrug, represents from now on an alternative
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