米非司酮用于紧急避孕137例临床观察

目的 探讨米非司酮用于紧急避孕的最佳剂量，用药方法及妇女月经周期之间的关系。方法 将无保护的性生活或避孕措施失败后７２小时内就来诊的，要求进行紧急避孕的健康育龄妇女分为二组，Ｉ组４６例，选择月经周期第１４天前，口服米非司酮２５ｍｇ；Ⅱ组９１例，选择月经周期第１５天后，口服米非司酮５０ｍｇ，分２次服用，间隔１２小时，结果 Ｉ组有１例妊娠，避孕成功率为７８．７％，Ⅱ组无妊娠发生，避孕成功率１００％

Clinieal Observation of Mifepristone in Emergent Contraeeption with 137 Cases Analysis

Objective To explore the best dosage of Mefipristone in emergent contraception and the relationship between the drug and menstrual cycle of the women. Methods Out of 137 cases who had unprotected sexual intercourse or failure of the contraceptive measures within 72 hours, two groups were divided: group I (46 cases ,15 days before the menstrual cycle) and II (91 cases, 15 days after the menstrual cycle ). All the cases in group I only took 25 mg Mefipristone twice a day while the cases in group II took 50 mg Mefipristone twice a day at the interval of 12 hours. Results Only one case in group I got pregnant with the effective rate of 75.7% while in group II there was no pregnancy at all. Conclusion 50 mg Mefipristone taken orally twice a day at the interval 0f 12 hours was the most effective way for emergent contraceptions.