利多卡因与罗哌卡因混合液用于肌间沟神经阻滞的研究

目的探讨利多卡因与罗哌卡因混合用于肌间沟神经阻滞的临床价值。方法将60例ASAⅠ~Ⅱ级接受肌间沟神经阻滞麻醉的患者随机分为3组,分别予以以下麻醉药物:0.5%罗哌卡因30 mL、1%利多卡因15 mL与0.5%罗哌卡因15 mL、1%利多卡因30 mL。记录3组患者阻滞起效时间及感觉阻滞持续时间。结果混合液组的阻滞起效时间慢于利多卡因组,快于罗哌卡因组;混合液组的感觉阻滞持续时间长于利多卡因组,短于罗哌卡因组。结论临床应用1%利多卡因15 mL与0.5%罗哌卡因15 mL在药效动力学上优势并不明显,需综合考虑手术、患者情况审慎使用。

A trial comparing 1% Lidocaine followed by 0.5% Ropivacaine to 1% Lidocaine for inter-scalene brachial plexus block

Objective To investigate the effect of mixture of Lidocaine and Ropivacaine. Methods Sixty patients undergoing arthroscopic shoulder surgery （ASA physical status Ⅰ-Ⅱ ） with interscalene brachial plexus block as the sole anesthetic were studied.The subjects were randomized to receive 1 of 3 study solutions：30ml of ropivacaine 0.5% ,a mixture of 15 ml lidocaine 1% and ropivacaine 0.5% , 30 mL of lidocaine 1%. The block onset time and duration of sensory block were assessed. Results Onset of block for the mixture of 15 ml lidocaine 1% and ropivacaine 0.5% faster than the group of ropivacaine 0.5% ,but slower than the group of lidocaine 1%. The duration of sensory block foe the mixture of 15 ml lidocaine 1% and ropivacaine 0.5% shorter than the the group of ropivacaine 0.5%, but longer than the group of lidocaine 1% .Conclusion There was no advantage for the mixture lidocaine 1% andropivacaine 0.5% in interscalene brachial plexus block.