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袖套法豚鼠至大鼠异种全胰十二指肠移植模型的建立
引用本文:李晓平,李朝龙,沈新明,蒋邦好. 袖套法豚鼠至大鼠异种全胰十二指肠移植模型的建立[J]. 南方医科大学学报, 2000, 20(1): 30-31
作者姓名:李晓平  李朝龙  沈新明  蒋邦好
作者单位:第一军医大学南方医院肝胆血管外科,广东,广州,510515
摘    要:目的为研究超急性排斥反应及对策,建立异种胰腺移植模型。方法以豚鼠和大鼠为供受者,用袖套法吻合静脉建立异种全胰十二指肠移植模型。结果共行 42次手术,成功 38例,均有内分泌功能,移植有效率为 100%。结论本模型具有操作简单,冷缺血及腹主动脉阻断时间短,不易形成血栓及吻合口漏等优点,为一较实用的研究异种胰腺移植模型。

关 键 词:全胰十二指肠移植  豚鼠  大鼠

Establishment of guinea pig to rat pancreaticoduodenal xenograft model
LI Xiao-ping,LI Chao-long,SHEN Xin-ming,JIANG Bang-hao. Establishment of guinea pig to rat pancreaticoduodenal xenograft model[J]. Journal of Southern Medical University, 2000, 20(1): 30-31
Authors:LI Xiao-ping  LI Chao-long  SHEN Xin-ming  JIANG Bang-hao
Affiliation:LI Xiao-ping,LI Chao-long,SHEN Xin-ming,JIANG Bang-hao Department of Hepatobiliary and Vascular surgery,Nanfang Hospital,First Military Medical University,Guangzhou 510515,China
Abstract:Objective To establish a guinea pig to rat pancreaticoduodenal xenograft model for studying hyperacute rejection. Methods Superior mesenteric vier-left renal vein cuff anastomases were resected. An end to side anastomasis was made between the graft duodenum and the host jejunum. Results Fortytwo operations were done, and 38 cases were successful, of which all grafts of the successful cases had endocrinium function. Conclusions This model can reduce the incidence of thrombosis and the duration of ischemia during operation. It is a simple and practical,
Keywords:pancreaticoduodenal xenograft  guinea pig  rat
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