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Ten years of experience in chronic ulcers and malignant transformation
Authors:Maria G Onesti  Pasquale Fino  Paolo Fioramonti  Vittoria Amorosi  Nicolò Scuderi
Affiliation:Department of Plastic, Reconstructive and Aesthetic Surgery, University of Rome “Sapienza”, Policlinico Umberto I, Rome, Italy
Abstract:Malignant degeneration of wounds is rare and often misdiagnosed. Delay in diagnosis may result in a worse prognosis. The aim of this study is to determine the number of skin cancers associated with chronic skin ulcers in our facility over a period of 10 years. Between January 2002 and December 2012, a total of about 1000 patients had consulted with us for chronic wounds, especially of vascular, diabetic and traumatic origin and pressure ulcers. Thirteen skin cancers had been detected: seven squamous cell and five basal cell carcinomas and one melanoma. We highlight how important it is to be aware of the signs suggesting a malignant change and the importance of biopsy at regular intervals during the life cycle of any chronic wound.
Keywords:Basal cell carcinoma  Chronic wound  Malignant transformation  Marjolin's ulcer  Squamous cell carcinoma
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