Increasing the low residue diet to 3 days does not improve the bowel cleansing in hard to prepare patients: Post hoc analysis of a randomized controlled trial |
| |
Authors: | Antonio Z. Gimeno-García Raquel de la Barreda-Heuser Cristina Reygosa Alberto Hernández Carla Amaral Isabel Mascareño David Nicolás-Pérez Alejandro Jiménez Antonio J. Lara Anjara Hernández Vanessa Felipe José Luis Baute Onofre Alarcon-Fernández Manuel Hernandez-Guerra Rafael Romero Inmaculada Alonso Yanira González Zaida Adrian Enrique Quintero |
| |
Affiliation: | 1. Servicio de Gastroenterología, Hospital Universitario de Canarias, Instituto Universitario de Tecnologías Biomédicas (ITB) & Centro de Investigación Biomédica de Canarias (CIBICAN), Departamento de Medicina Interna, Universidad de La Laguna, Spain;2. Servicio de Endocrinología y Nutrición, Hospital San Juan de Dios, Santa Cruz de Tenerife, Spain |
| |
Abstract: | BackgroundRecent evidence suggests that the number of low residue diet (LRD) days does not influence the bowel cleansing quality in non-selected patients. However, there are not data in the subgroup of patients with risk factors of inadequate bowel cleansing.ObjectiveThe aim of this study was to assess whether a 3-day LRD improved the bowel cleansing quality in patients with risk factors of poor bowel cleansing.Patients and methodsPost hoc analysis of a randomized controlled trial carried out between December 2017 and March 2018 in a tertiary care hospital. Patients with high risk of poor bowel cleansing were selected following a validated score. The patients were randomized to the 1-day LRD or 3-day LRD groups. All patients received a 2-L split-dose of polyethylene glycol plus ascorbic acid. Intention-to-treat (ITT) and per-protocol (PP) analyses were conducted for the main outcome.Results135 patients (1-day LRD group = 67, 3-day LRD = 68) were included. The rate of adequate cleansing quality was not significantly different between the groups in the ITT analysis: 76.1%, 95% CI: [64.6–84.8] vs. 79.4%, 95% CI: [68.2–87.4]; odds ratio (OR) 1.2, 95% CI [0.54–2.73]) or in the PP analysis: 77.3%, 95% CI: [65.7–85.8] vs. 80.3%, 95% CI: [69.0–88.3]; OR 1.2, 95% CI [0.52–2.77]). Compliance with the diet or cleansing solution, satisfaction or difficulties with the LRD and the polyp/adenoma detection rates were not significantly different.ConclusionOur results suggest that 1-day LRD is not inferior to 3-day LRD in patients with risk factors of inadequate bowel cleansing. |
| |
Keywords: | Low-residue diet Risk factors of poor bowel cleansing Boston Bowel Preparation Scale Colonoscopy Predictive score Dieta baja en residuos Factores de riesgo de limpieza intestinal deficiente Escala de preparación intestinal de Boston Colonoscopia Puntuación predictiva |
本文献已被 ScienceDirect 等数据库收录! |
|