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Autoantibody Detection for Diagnosis in Direct Immunofluorescence-Negative Mucous Membrane Pemphigoid: Ocular and Other Sites Compared
Authors:John Dart  Jane Setterfield  Richard W Groves  John B Mee  Gilles FH Diercks  Hendri H Pas  Darwin Minassian
Institution:1. Moorfields Eye Hospital NHS Foundation Trust and the UCL Institute of Ophthalmology, London, United Kingdom;2. Guy’s and St. Thomas’s NHS Foundation Trust and King’s College London, London, United Kingdom;3. St. John’s Institute of Dermatology, Viapath Analytics LLP, St. Thomas’ Hospital, London, United Kingdom;4. Division of Genetics and Molecular Medicine, King’s College London, Guy’s Hospital, London, United Kingdom;5. Department of Pathology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands;6. Center for Blistering Diseases, Department of Dermatology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands;7. Epivision (Ophthalmic Epidemiology Consultants), Penn, United Kingdom
Abstract:
Keywords:BP180-NC16a  BP230  Diagnosis  Direct immunofluorescence  Enzyme-linked immunosorbent assay  Indirect immunofluorescence  Laminin 332  Mucous membrane pemphigoid  Ocular and extraocular pemphigoid  Prospective cross-sectional study  Sensitivity  Serology  Specificity  BM"}  {"#name":"keyword"  "$":{"id":"kwrd0080"}  "$$":[{"#name":"text"  "_":"basement membrane  DIF"}  {"#name":"keyword"  "$":{"id":"kwrd0090"}  "$$":[{"#name":"text"  "_":"direct immunofluorescence  DIF+"}  {"#name":"keyword"  "$":{"id":"kwrd0100"}  "$$":[{"#name":"text"  "_":"direct immunofluorescent positive  DIF–"}  {"#name":"keyword"  "$":{"id":"kwrd0110"}  "$$":[{"#name":"text"  "_":"direct immunofluorescent negative  ELISA"}  {"#name":"keyword"  "$":{"id":"kwrd0120"}  "$$":[{"#name":"text"  "_":"enzyme-linked immunosorbent assay  IIF"}  {"#name":"keyword"  "$":{"id":"kwrd0130"}  "$$":[{"#name":"text"  "_":"indirect immunofluorescence  IgA"}  {"#name":"keyword"  "$":{"id":"kwrd0140"}  "$$":[{"#name":"text"  "_":"immunoglobulin A  IgG"}  {"#name":"keyword"  "$":{"id":"kwrd0150"}  "$$":[{"#name":"text"  "_":"immunoglobulin G  MMP"}  {"#name":"keyword"  "$":{"id":"kwrd0160"}  "$$":[{"#name":"text"  "_":"mucous membrane pemphigoid  SSS"}  {"#name":"keyword"  "$":{"id":"kwrd0170"}  "$$":[{"#name":"text"  "_":"salt-split skin
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