| 炎症反应中组织损伤机制的探讨：中性粒细胞... |
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| 引用本文： | 崔晓岚 崔莲仙. 炎症反应中组织损伤机制的探讨：中性粒细胞...[J]. 中国医学科学院学报, 1991, 13(2): 90-95 |
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| 作者姓名： | 崔晓岚 崔莲仙 |
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| 摘 要： | ![]()
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| 关 键 词： | 中性粒细胞 化学发光 脱颗粒 炎症 |
Stimulated chemiluminescence and degranulation of human polymorphonuclear leukocytes: possible involvement in the mechanisms of tissue damage during inflammation] |
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| X Cui. Stimulated chemiluminescence and degranulation of human polymorphonuclear leukocytes: possible involvement in the mechanisms of tissue damage during inflammation][J]. Acta Academiae Medicinae Sinicae, 1991, 13(2): 90-95 |
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| Authors: | X Cui |
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| Affiliation: | Institute of Basic Medical Sciences, Beijing. |
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| Abstract: | ![]()
A significant increase of polymorphonuclear leukocytes (PMN) chemiluminescence (CL) was observed when PMN was treated with rat C5ades Arg (r-C5ai), FMLP, opsozined zymosan (STZ) or a calcium ionophore A23487 separately. These stimuli, as well as aggregated IgG (A-IgG), could also cause the release of beta-glucuronidase (beta-g) and myeloperoxidase (MPO) from PMN, on the other hand, elastase (NE) release was not noticed when PMN was treated with r-C5ai and FMLP, which generally stimulated PMN in a cytochalasin B-dependent manner. These results suggest that the kinetics of PMN CL and degranulation vary depending upon the stimulus. |
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