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1.6-氨基辛二酸-8-精-催产素对电针镇痛的影响
引用本文:宋朝估 刘文彦. 1.6-氨基辛二酸-8-精-催产素对电针镇痛的影响[J]. 针刺研究, 1992, 17(3): 171-174
作者姓名:宋朝估 刘文彦
作者单位:第二军医大学神经生物学教研室,济宁医学院生理教研室,第二军医大学神经生物学教研室,第二军医大学神经生物学教研室 上海 200433,济宁市 272113,上海 200433,上海 200433
摘    要:<正> 8-精-催产素(8-arginine-vasotocin,AVT)又名管催产素,是松果体分泌的九肽激素,其环状结构部分与催产素(oxytocin,OT)相同,直链部分与精氨酸加压素(Argi-

关 键 词:电针 止痛 催产素 管催产素

Effect of Asu-AVT on electroacupuncture (EA) analgesia]
C Song,W Y Liu,C Wang,B Lin. Effect of Asu-AVT on electroacupuncture (EA) analgesia][J]. Acupuncture research, 1992, 17(3): 171-174
Authors:C Song  W Y Liu  C Wang  B Lin
Affiliation:Department of Neurobiology, Second military Medical University, Shanghai.
Abstract:The Asu-AVT (1,6-aminosuberic acid -8-arginine-vasotocin) in an analogue of 8-arginine-vasotocin (AVT) which is one of pineal hormones. The effect of Asu-AVT on the pain threshold and EA analgesia was studied in rats. An increase of 16.2-41.5% in pain threshold was observed within 70 min. after ivc of Asu-AVT (75ng), while the Asu-AVT injection in combination with EA produced a significant increase of 164.6-309.1% in pain threshold, which was much higher than that in the saline-EA group (p < 0.05-0.01). The effect of Atu-AVT is analogous to that of oxytocin and arginine-vasopressin. The data indicate ivc of ASu-AVT not only elevates the pain threshold, but also enhances the EA analgesia. These results suggest that the pineal hormone, AVT may play a role in the EA analgesia.
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