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非酒精性脂肪肝相关危险因素分析
引用本文:孙建光,吕霞霞.非酒精性脂肪肝相关危险因素分析[J].中医临床研究,2011,0(18):111-113.
作者姓名:孙建光  吕霞霞
作者单位:山东中医药大学,山东济南,250014
基金项目:山东省高等学校科技计划项目
摘    要:目的:通过流行病学调查,分析NAFLD的相关危险因素,为NAFLD的防治提供理论依据。方法:805人依据体检情况分为NAFLD组和非NAFLD组。所得数据用SPSS15.0软件包进行统计,计量资料行t检验,计数资料行x2检验,患病率随年龄升高趋势行线性趋势检验,多因素分析采用Logistic回归分析。分析年龄、性别、BMI、血压、血脂、血糖等因素与NAFLD的相关性。结果:①男性NAFLD患病率(30.58%)大于女性患病率(19.49%)(P〈0.01);女性NAFLD患病率随年龄增长呈升高趋势(P〈0.01)。②对NAFLD危险因素指标进行Logistic多因素逐步回归分析,结果显示TG、BMI、FBG、性别(男性)、DBP是NAFLD形成的主要危险因素。结论:NAFLD形成的主要危险因素包括TG、BMI、FBG、DBP、性别(男性)。

关 键 词:非酒精性脂肪肝  危险因素  疗效

Analysis on risk factors of non-alcoholic fatty liver disease
Abstract:Objective:Based on epidemiological investigations,analyzds the relative risk factors of NAFLD,thus providing theoretical reference for the control of NAFLD.Methods:Following the medical check results,805 subjects were divide into non-NAFLD group and NAFLD group.Data obtained were statistically processed with SPSS15.0.Numerical data were analyzed with t test,qualitative data were analyzed with chi-square test,the tendency of sick rate rising with age were analyzed with linear trend test,multi-factors were analyzed with Logistic regression.Analyzed The relations of NAFLD with factors including age,sex,BMI,blood pressure,blood-lipid, blood sugar.Results:①Men’s sick rate of NAFLD(30.58%)is higher than that of women(19.49%)(P〈0.01);Women’s sick rates show a tendency of increasing with age(P〈0.01).②Making Logistic multivariate regression analysis for indicators of NAFLD risk factors,the result indicate that TG,BMI,FBG,gender(male)and DBP are major risk factors leading to NAFLD.Conclusion:Major risk factors leading to NAFLD include TG,BMI,FBG,DBP and gender(male).
Keywords:Non-alcoholic fatty liver disease  Risk factors  Effect
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