| 黏液纤维肉瘤7例临床病理分析 |
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| 引用本文： | 王占东,杨杰,杨会钗,王小玲,郭明,吴国祥.黏液纤维肉瘤7例临床病理分析[J].临床与实验病理学杂志,2008,24(6). |
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| 作者姓名： | 王占东 杨杰 杨会钗 王小玲 郭明 吴国祥 |
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| 作者单位： | 1. 河北医科大学第四医院病理科,石家庄,050011
2. 河北体育学院运动人体科学系,石家庄,050041 |
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| 基金项目： | 河北省普通高校强势特色学科资助 |
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| 摘 要： | 目的 探讨黏液纤维肉瘤临床病理特点。方法收集7例黏液纤维肉瘤患者的临床及病理资料，并对手术切除的标本进行多种抗体免疫组织化学染色，抗体包括CD117、CD34、CD99、actin、S-100蛋白、vimentin等。结果黏液纤维肉瘤多见于男性，年龄37～72岁，中位年龄52岁，主要以不完全纤维性间隔的多结节行为为特征性表现，黏液区与细胞密集区交错排列，细胞密集区可见特征性曲线型血管，肿瘤细胞围绕在其周围排列。免疫表型：vimentin、CD99阳性，其他抗体多呈阴性。结论黏液纤维肉瘤为一侵袭性较强的软组织肉瘤，与多种黏液性肿瘤需要鉴别，易局部复发，宜采取以手术切除为主的综合性治疗。
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| 关 键 词： | 软组织肿瘤 黏液纤维肉瘤 临床病理 免疫组织化学 |
Clinicopathologic features of myxofibrosarcoma: a report of 7 cases |
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| WANG Zhan-dong,YANG Jie,YANG Hui-chai,WANG Xiao-ling,GUO Ming,WU Guo-xiang.Clinicopathologic features of myxofibrosarcoma: a report of 7 cases[J].Chinese Journal of Clinical and Experimental Pathology,2008,24(6). |
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| Authors: | WANG Zhan-dong YANG Jie YANG Hui-chai WANG Xiao-ling GUO Ming WU Guo-xiang |
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| Institution: | 1Department of Pathology;the Fourth Hopital of Hebei Medical University;Shijiazhuang 050011;China;2Department of Human Movement Science;Hebei Sports Insitutue College;Shijiazhuang 050041;China |
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| Abstract: | Purpose To investigate the clinical and pathologic features of myxofibrosarcoma. Methods Clinicopathologic data were collected in 7 cases of myxofibrosarcoma. All specimens were stained by immunohistochemical method with a panel of antibodies including CD117, CD34, CD99, actin, S-100 and vimentin. Results Myxofibrosarcoma predominantly affected male patients. Age ranged from 37 to 72 years old (mean 52). The tumor cells showed a multinodular growth pattern and were all characterized by alternation between h... |
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| Keywords: | soft tissue neoplasms myxofibrosarcoma pathologic immunohistochemistry |
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