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Cellular retinol-binding protein in normal and neoplastic human mammary gland
Authors:Fex  G.  Linell  F.  Ljungberg  O.
Affiliation:(1) Department of Clinical Pathology, University of Lund, Malmö General Hospital, S-214 01 Malmö, Sweden;(2) Dept of Clinical Chemistry, University of Lund, Malmö General Hospital, S-214 01 Malmö, Sweden
Abstract:
The concentration of cellular retinol-binding protein (CRBP) was determined in samples of normal and neoplastic mammary gland, using a specific and sensitive radioimmunoassay. The CRBP concentration was significantly higher in neoplastic tissue, but detectable levels were also present in all samples of normal gland. Tubulo-ductal cancers had significantly lower CRBP levels than other cancer types. The CRBP concentration of the neoplastic tissue showed no correlation with the concentration of progesterone or estrogen receptor.
Keywords:cellular retinol-binding protein  mammary cancer
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