Cellular retinol-binding protein in normal and neoplastic human mammary gland |
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Authors: | Fex G. Linell F. Ljungberg O. |
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Affiliation: | (1) Department of Clinical Pathology, University of Lund, Malmö General Hospital, S-214 01 Malmö, Sweden;(2) Dept of Clinical Chemistry, University of Lund, Malmö General Hospital, S-214 01 Malmö, Sweden |
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Abstract: | The concentration of cellular retinol-binding protein (CRBP) was determined in samples of normal and neoplastic mammary gland, using a specific and sensitive radioimmunoassay. The CRBP concentration was significantly higher in neoplastic tissue, but detectable levels were also present in all samples of normal gland. Tubulo-ductal cancers had significantly lower CRBP levels than other cancer types. The CRBP concentration of the neoplastic tissue showed no correlation with the concentration of progesterone or estrogen receptor. |
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Keywords: | cellular retinol-binding protein mammary cancer |
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