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| 慢性乙型肝炎患者外周血T细胞亚群及T_4/T_8双标志细胞的初步研究 | |
| 引用本文： | 胡国强,郝连杰. 慢性乙型肝炎患者外周血T细胞亚群及T_4/T_8双标志细胞的初步研究[J]. 中国免疫学杂志, 1988, 0(5) |
| 作者姓名： | 胡国强 郝连杰 |
| 作者单位： | 同济医科大学附属同济医院传染病学教研室 武汉(胡国强)，同济医科大学附属同济医院传染病学教研室 武汉(郝连杰) |
| 摘 要： | 本文应用抗人T细胞单克隆抗体借助葡萄球菌-羊红细胞直接双花环法研究了11例慢性乙型肝炎患者外周血T细胞亚群.结果发现.慢性乙型肝炎患者外周血T_4~+细胞(辅助/诱导T细胞)数在正常范围;T_8~+细胞抑制/细胞毒T细胞数与正常对照比较明显增加;T_4/T_8比值与正常对照比较明显降低.此外。在慢性乙型肝炎患者外周血中发现有较多的可同时表达T_4和T_8抗原的细胞。其功能和意义尚待进一步研究. |
| 关 键 词： | 乙型肝炎 T细胞亚群 单克隆抗体 双标志细胞 |
PRELIMINARY STUDY OF T CELL SUBSETS AND T4/T8 DOUBLE LABELED CELLS IN CHRONIC HEPATITIS B PATIENTS |
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| Hu Guo Qiang,Hao Lian Jie. PRELIMINARY STUDY OF T CELL SUBSETS AND T4/T8 DOUBLE LABELED CELLS IN CHRONIC HEPATITIS B PATIENTS[J]. Chinese Journal of Immunology, 1988, 0(5) | |
| Authors: | Hu Guo Qiang Hao Lian Jie |
| Affiliation: | Hu Guo Qiang,Hao Lian Jie Department of Infectious Diseases Tong Ji Hospital,Tong J i Medical University,Wu Han City |
| Abstract: | 11 patients with chronic hepatitisB virus(HBV)infection were studiedby enumeration of T cell subsetsin peripheral blood withStaphylococco-SRBC DoubleRosette Forming Technique.It was found that T_3~+ cell subsetwas higher and T_4/T_8 ratio was sig-nificantly lower in patients withchronic HBV infection than in con-rol and higher numbers of doublelabeled cells (expressing both T_4 andT_8 antigens) were also found in pa-tients with chronic HBV infection. |
| Keywords: | HBV Infection T Cell Subset Double Labeled Cell |
| 本文献已被 CNKI 等数据库收录！ | |