| 氟他胺治疗前列腺癌的Ⅱ期临床观察 |
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| 引用本文： | 赵体平,姚育梅,张永康,黄翼然,氟他胺临床协作小组,姚笃卿,严伟民,闻小英,沈慷. 氟他胺治疗前列腺癌的Ⅱ期临床观察[J]. 中国临床药学杂志, 1995, 0(2) |
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| 作者姓名： | 赵体平 姚育梅 张永康 黄翼然 氟他胺临床协作小组 姚笃卿 严伟民 闻小英 沈慷 |
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| 作者单位： | 上海医科大学肿瘤医院，上海医科大学肿瘤医院，上海医科大学中山医院，上海第二医科大学仁济医院，上海医科大学红旗制药厂，上海医科大学红旗制药厂，上海医科大学红旗制药厂，上海医科大学红旗制药厂 200032，200032，200032，200001，200032，200032，200032，200032，200032 |
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| 摘 要： | 氟他胺是非甾体类雄激素拮抗剂,用于治疗前列腺癌100例,采用美国生产缓退瘤(Fugerel)治疗前列腺癌31例作为对照组。结果氟他胺组有效率86％,缓退瘤组有效率87.09％,两组无显著差异,均无明显不良反应,结果表明氟他胺是一种治疗前列腺癌较满意药物。
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| 关 键 词： | 氟他胺 Ⅱ期临床试验 前列腺癌 |
PHASE I CLINICAL TRIAL OF FLUTAMIDE IN THE TREATMENT OF PROSTATIC CARCINOMA |
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| ZHAO Ti-ping YAOYu-mei ZHANG Yong-kang HUANG Yi-ran. PHASE I CLINICAL TRIAL OF FLUTAMIDE IN THE TREATMENT OF PROSTATIC CARCINOMA[J]. Chinese Journal of Clinical Pharmacy, 1995, 0(2) |
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| Authors: | ZHAO Ti-ping YAOYu-mei ZHANG Yong-kang HUANG Yi-ran |
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| Abstract: | Flutamide is a nonsteroidal antiandrogen and is used to treat prostatic cancer. This study compared Flutamide tablet and Fugerel (Schering Plough Carp, USA) in the treatment of Prostatic cancer (100 cases for Flutamide V. S. 31 cases for Fugerel). The statistical analysis revealed no significant difference with respect to response rates (Flutamide 86% , Fugerel 87. 09% respectivelly)and no obvious adverse reaction was found. These data indicate that Flutamide is an effective and save agent in the management of patients with pro-static cancer. |
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