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正常人表皮郎格罕氏细胞和未定类细胞表面标记的研究
引用本文:张凯福建医学院,陈树藩,沈云英,王大中. 正常人表皮郎格罕氏细胞和未定类细胞表面标记的研究[J]. 福建医科大学学报, 1991, 0(2)
作者姓名:张凯福建医学院  陈树藩  沈云英  王大中
作者单位:病理解剖学教研组,福建医学院病理解剖学教研组,福建医学院病理解剖学教研组,福建省皮肤病防治院
摘    要:
应用单抗Leu-6和Ia(HLA-DR)以免疫组化ABC法对7例正常表皮内郎格罕氏细胞和未定类细胞的比较观察,发现Leu-6(+)细胞与Ia(+)细胞数量比为2:1(P<0.001)。Leu-6作为该类细胞的表面标记在敏感性和特异性方面均优于Ia单抗,提示表皮内郎格罕氏细胞和未定类细胞存在Ia(+)/Leu-6(+)和Ia(-)/Leu-6(+)两亚类。

关 键 词:郎格罕氏细胞  免疫组化

Study on Surface Marker of Langerhans Cells and Indeterminate Cells in Human Epidermis
Zhang Kai,Chen Shufan,Shen Yunying,et al. Study on Surface Marker of Langerhans Cells and Indeterminate Cells in Human Epidermis[J]. Journal of Fujian Medical University, 1991, 0(2)
Authors:Zhang Kai  Chen Shufan  Shen Yunying  et al
Abstract:
Langerhans cells and indeterminate cells were studied in seven cases of human normal epidermidesy the use of two kinds of monoclonal antibodies,anti-Leu-6 and anti-la,and ABC immunohistochemical techniques. The results indicate that Leu-6 is more sensitive and spicific as a surface marker of Langerhans cells and indeterminate cells than Ia. Meanwhile it shows that there are two subsets, la (+)/Ler-6 (+)and la(+)/Leu-6(+),in the Langerhans cells and indeterminate cells.
Keywords:epidermis Langerhans cell  immunohistoehemistry
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