| Child-Turcotte-Pugh评分与终未期肝病模型对晚期肝癌患者围介入术期的预后评估 |
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| 引用本文： | 魏建,李洪璐,郭江,李常青.Child-Turcotte-Pugh评分与终未期肝病模型对晚期肝癌患者围介入术期的预后评估[J].中国介入影像与治疗学,2016,13(10):596-599. |
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| 作者姓名： | 魏建 李洪璐 郭江 李常青 |
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| 作者单位： | 首都医科大学附属北京地坛医院肿瘤介入科, 北京 100015,首都医科大学附属北京地坛医院肿瘤介入科, 北京 100015,首都医科大学附属北京地坛医院肿瘤介入科, 北京 100015,首都医科大学附属北京地坛医院肿瘤介入科, 北京 100015 |
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| 摘 要： | 目的探讨Child-Turcotte-Pugh(CTP)评分与终未期肝病模型(MELD)预测晚期肝癌围介入手术期患者生存期的优缺点及互补性。方法收集100例晚期肝癌患者,均行TACE,术前根据MELD公式计算患者的MELD值,并同时计算CTP评分。应用ROC曲线及其曲线下面积(AUC)分析并比较MELD、CTP评分预测患者生存时间的价值。结果采用CTP评分判断患者TACE术前、术后3、6个月生存期的的AUC分别为0.540、0.754、0.889,而采用MELD评分时分别为0.682、0.701、0.801。2种模型判断患者生存时间的AUC差异均有统计学意义(P均0.05)。结论在判断晚期肝癌短期预后方面,MELD与CTP评分均为较好的指标。
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| 关 键 词： | 肝肿瘤 肝动脉化疗栓塞术 终未期肝病模型 生存期 |
| 收稿时间： | 2016/3/15 0:00:00 |
| 修稿时间： | 2016/6/27 0:00:00 |
Child-Turcotte-Pugh score and model for end-stage liver disease in judging prognosis of advanced hepatocellular carcinoma in peri-inventional period |
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| WEI Jian,LI Honglu,GUO Jiang and LI Changqing.Child-Turcotte-Pugh score and model for end-stage liver disease in judging prognosis of advanced hepatocellular carcinoma in peri-inventional period[J].Chinese Journal of Interventional Imaging and Therapy,2016,13(10):596-599. |
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| Authors: | WEI Jian LI Honglu GUO Jiang and LI Changqing |
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| Institution: | Department of Oncology of Interventional Radiology, Beijing Ditan Hospital of Capital Medical University, Beijing 100015, China,Department of Oncology of Interventional Radiology, Beijing Ditan Hospital of Capital Medical University, Beijing 100015, China,Department of Oncology of Interventional Radiology, Beijing Ditan Hospital of Capital Medical University, Beijing 100015, China and Department of Oncology of Interventional Radiology, Beijing Ditan Hospital of Capital Medical University, Beijing 100015, China |
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| Abstract: | Objective To compare the value of Child-Turcotte-Pugh (CTP) score and model for end-stage liver disease (MELD) in judging prognosis of advanced hepatocellular carcinoma in peri-inventional period. Methods Totally 100 patients with hepatocellular carcinoma were collected and underwent TACE. Before TACE, the MELD value for each patient were calculated according to MELD formula, and at the same time CTP score were calculated. The value of MELD and CTP score in judging the prognosis of patients with advanced hepatocellular carcinoma were analyzed and compared by the ROC curves and the area under the curve (AUC). Results The AUC of CTP score in judging survival time before and 3, 6 months after TACE were 0.540, 0.754, 0.889, while the AUC of MELD was 0.682, 0.701, 0.801, and the differences were statistically significant (all P<0.05). Conclusion MELD score is a method as good as CTP in judging the prognosis of advanced liver cancer. |
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| Keywords: | Liver neoplasmas Transcatheter arterial chemoembolization Model for end-stage liver disease Overall survival |
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