泌尿生殖道支原体感染检测及药敏试验

目的了解本地区泌尿生殖道解脲脲原体（Uu）和人型支原体（Mh）的感染状况及药物敏感性，指导临床医生合理应用抗生素。方法应用法国生物梅里埃公司提供的IST试剂盒进行支原体鉴定及9种药物敏感检测，并对结果进行统计学分析。结果2410例门诊患者中检出支原体阳性者共1401例，总感染率为58．1％，其中Uu单独感染901例（占37．4％），Mh感染85例（占3．5％），Uu＋Mh混合感染415例（占17．2％）。交沙霉素和原始霉素敏感率最高，对Uu感染分别是98．8％和98．8％，对Uu＋Mh混合感染分别为86．9％和86．8％；环丙沙星敏感率最低，分别是6．4％和2．6％。结论支原体感染以Uu为主，交沙霉素和原始霉素敏感率最高，环丙沙星敏感率最低。临床应选用培养敏感的抗菌药物，提高治疗效果。

Detection and susceptibility to antibiotics of Mycoplusma in genitourinary tract

Objective To investigate infection statue and antibiotic susceptibility of Mycoplasma urealyticum and Mycoplasma hominis in the genitourinary tract in our area, so as to instruct the rational use of antibiotics. Methods Genitourinary secretions were collected with swabs. They were cultured with the diagnostic kit of Mycoplasma (Biomerieux Company) to detect M. urealyticum and M. hominis. Meanwhile the susceptibility of Mycoplasma against 9 antimicrobial agents was tested with the same kit. According to the manual of the kit,the results were read. The data were statistically analyzed. Results A total of 2 410 samples were collected, and the positive rate was 58. 1%. Among 1410 positive cases of Mycoplasma, 901 cases were M. urealyticum (37.4%), 85 were M. hominis (3.5%), and 415 were M. urealyticum combined with M. hominis (17.2%).The susceptibility rate of M. urealyticum to josamycin, pristinamycin, ciprofloxacin was 98. 8%, 98. 8% and 6. 4% respectively, while the susceptibility rate of M. urealyticum combined with M. horninis was 86.9%,86. 8% and 2.6% respectively. Conclusion M. urealyticum is the major cause of Mycoplasma infection in genitourinary system. Josamycin and pfistinamycin are more effective than other antimicrobial agents to treat Mycoplasma irffection. Ciprofloxacin is more resistant than other antimicrobial agents. Sensitive antibiotics should be selected based on the results of bacterial culture and drug sensitivity tests so as to raise the clinical curative effects.