出血性脑卒中发病危险因素的病例对照研究

[目的]探索出血性脑卒中发病因素中可以干预的一些因素,为进一步降低脑卒中的发病率和病死率奠定基础。[方法]对2004年在广东省人民医院等6家医院住院的358例出血性脑卒中病人,按1∶1选取对照,进行条件Lo-gistic回归分析,进行病例对照研究。[结果]单因素分析结果表明,出血性脑卒中发病的危险因素是BMI>24、高血压史、病前血压波动、高脂血症史、高胆固醇血症史、高血压家族史、吸烟、高尿酸血症、饮食口味重和低密度脂蛋白升高,而血压波动、高血脂症史进入多因素条件Logistic回归模型(OR值分别为27.92和10.23)。[结论]出血性脑卒中的防治需采取综合干预措施,重点是控制血压及血脂,其次是改变不良的生活方式和饮食习惯,保持良好的精神心理状态。

The Case-Control Study on the Risk Factors of Bleeding Stroke

[Objective]To explore the risk factors of bleeding st roke in order to found a good basis to prevent and control the occurrence of ble eding stroke.[Methods]The case group contained 358 bleeding s troke persons.A 1 to 1 matched case-control study was used according to age,ge nder,nation,registered hospitals in Guangzhou in 2004.The conditional logistic regression model was performed in this study.[Results]Hyperli pemia and the fluctuation of blood pressure entered the multiple conditional log istic regression model,and their OR were 27.92(95%CI4.66-167.20) and 10.23(95%CI2.41-43.41)respectively.[Conclusion]It is necessary to implement a comprehensive prevention program,such as keeping blood pressure and lipid tranquilization,lifestyle and dietary habit modification,kee ping good psychosis preservation.