42例早期梅毒临床及治疗分析

目的：进一步了解早期梅毒的临床特征和治疗效果。方法：对42例早期梅毒患者的临床资料及治疗效果进行分析。结果：42例患者中一期梅毒11例，二期梅毒18例，早期潜伏梅毒13例，RPR、TPHA检查均阳性。患者经治疗后皮疹消退，苄星青霉素治疗者RPR 1年均转阴。结论：多数一、二期梅毒都有典型皮疹，长效青霉素是治疗梅毒的首选药物，早期潜伏梅毒是防治的重点。

Clinical analysis and therapeutic results of 42 patients with early syphilis

Objective To review the clinical characteristics and therapeutic results of early syphilis.?Methods The clinical materials, results of the rapid plasma reagin circle card test (RPR) and treponema pallidum hemagglutination test (TPHA),and the therapeutic results of 42 cases of early syphilis were analysed.?Results Among the 42 patients, 11(26.2%) were diagnosed as primary syphilis,18 (42.9%) secondary syphilis and 13(30.9%) early latent syphilis. RPR and TPHA were positive in all patients. The syphilitic rash disappeared after benzathine penicillin G treatment, and the RPR turned to negative within one year.?Conclusion There are typical skin lesions in primary and secondary syphilis. The long-acting penicillin is recommended as the first choice therapy for syphilis. Prevention and control of the disease should be focused on early latent syphilis.