肛管直肠恶性黑色素瘤23例

笔者报告了1975～2008年本院收治的经病理证实的肛管直肠恶性黑色素瘤（ARMM）23例。对23例ARMM患者分别行根治性切除术（Mile’s术）和局部切除术及冰冻治疗,术后并辅以放疗、化疗、及生物治疗。19例患者获随访,随访时间8个月～5年。随访结果,Milers术组中位生存期为25.4个月,局部切除组及冰冻治疗组中位生存期为11个月,化疗组中位生存期为6个月。作者认为患者生存率的关键是早期治疗。并对ARMM的病因、临床诊断及其治疗进行了讨论。

Anorectic Malignant Melanoma: report of 23 cases

23 cases of anorectic malignant melanoma （ARMM） diagnosed pathologically were treated in our hospital from 1975 to 2008. These patients were treated with radical operation （Mile＇ s operation） and local resection and frozen therapy, plus chemotherapy, biological therapy and radiotherapy respectively. 18cases were followed up from eight months up to six years. The results showed that the median survival time was 25.4 months in the group of Mile＇ s, 11 months of local resection and 6 months in chemotherapy respectively. The authors considered that early diagnoses and treatment are the key to raise the survival rate. The causes of ARMM , clinic diagnosis, and its treatment were also discussed in the article.