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Multiple peripheral pulmonary nodules preceding rheumatoid arthritis
Authors:H. G. Nüsslein  W. Rödl  J. Giedel  M. Missmahl  J. R. Kalden
Affiliation:(1) Institute of Clinical Immunology and Rheumatology, University of Erlangen-Nürnberg, Krankenhausstrasse 12, D-8520 Erlangen, Federal Republic of Germany;(2) Department of Radiology, Clinic of Internal Medicine, University of Erlangen-Nürnberg, Krankenhausstrasse 12, D-8520 Erlangen, Federal Republic of Germany;(3) Department of Clinical Pathology, Clinic of Surgery, University of Erlangen-Nürnberg, Krankenhausstrasse 12, D-8520 Erlangen, Federal Republic of Germany
Abstract:
Summary The case of a young woman is reported, presenting multiple peripheral lung nodules, preceding the onset of classical rheumatoid arthritis 3 months later. The nodules observed seemed to be of pleural origin because they all had contact with the pleura which was partly thickened as demonstrated by computer-assisted tomography. The histopathology of material obtained by an open-lung biopsy revealed rheumatoid necrobiotic nodules. Although very rare, rheumatoid arthritis should be considered as a differential diagnosis of pulmonary nodules of unknown origin.
Keywords:Rheumatoid arthritis  Lung manifestations  Pulmonary nodules
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