| 肿瘤微血管密度与肝癌病理及预后关系 |
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| 引用本文： | 邹冬梅,杨清绪,武彤彤. 肿瘤微血管密度与肝癌病理及预后关系[J]. 中国基层医药, 2006, 13(11): 1840-1842 |
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| 作者姓名： | 邹冬梅 杨清绪 武彤彤 |
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| 作者单位： | 1. 516001,广东省惠州,惠州(东江)病理学会病理诊断部
2. 516001,广东省惠州中心医院病理科 |
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| 摘 要： | 目的 探讨肿瘤微血管密度（MVD）与肝细胞性肝癌临床病理及预后的关系。方法对30例肝细胞性肝癌根治性切除病理组织切片进行苏木精伊红染色．并用CD34单克隆抗体进行免疫组化染色，计数被CD34抗体染色的肿瘤血管内皮细胞数，以测定MVD。对MVD与临床病理因素及术后生存率关系进行分析。结果 单因素分析结果表明．MVD水平与肿瘤大小、TNM分期都是影响肝细胞性肝癌预后的因素；多因素分析结果表明．肝癌大小及肿瘤分期是肝细胞性肝癌独立预后因素。结论 MVD是肝细胞性肝癌一种预后因素。
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| 关 键 词： | 微血管密度 肝肿瘤 预后 |
| 收稿时间： | 2006-08-28 |
| 修稿时间： | 2006-08-28 |
Relationship between intra-tumor micro vessel density and clinic opathological features in patients with hapatocellular carcinoma |
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| ZOU Dong-mei,YANG Qing-xu,WU Tong-tong. Relationship between intra-tumor micro vessel density and clinic opathological features in patients with hapatocellular carcinoma[J]. Chinese Journal of Primary Medicine and Pharmacy, 2006, 13(11): 1840-1842 |
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| Authors: | ZOU Dong-mei YANG Qing-xu WU Tong-tong |
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| Affiliation: | Department of Pathology, Huizhou Pathology Academy, Huizhou , Guangdong 516001, China |
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| Abstract: | Objective To study the relationship between intra-tumor micro vessel density (MVD) clinic opathological features and prognosis of patients with hapatocellular carcinoma(HCC). Methods 30 cases of pathological sections undergone radical surgery for HCC,were evaluated after HE staining and anti-CD 34 monoclonal antibody immuno-histochemical staining. The number of endothelia cells stained by anti-CD34 antibody was counted. The relationship between MVD and survival rate afte roperation was evaluated. Results The surviva Irate was significantly lower in the tumor of larger size, poor stage and higher MVD than that in the other group(P< 0. 05). Conclusion MVD is one of the prognostic factors fo rHCC. |
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| Keywords: | Micro vessel density Liver neoplasms Prognosis |
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