腹腔内残留胆道结石转归的实验研究

目的 探讨胆道结石遗留腹腔的转归。方法 将腹腔镜胆道手术中所取结石及胆汁进行细菌培养 药敏和结石成份分析。在无菌条件下将结石置于51只Wistar大鼠腹腔内，3个月后处死存活大鼠，观察腹腔结石情况并取结石周围组织做病理学检查。结果 大鼠腹壁切口排出结石1只，3个月内死亡8只，死亡原因分别为腹腔感染，腹腔脓肿，肠瘘和肠梗阻，另43只大鼠的结石均被大网膜包绕，病理学检查结果为结石周围组织内有灶性脓肿形成。结论 腹腔残石对机体有害，腹腔镜胆道手术应避免结石遗留腹腔。

An experimental study on the effect of lost gallstones in peritoneal cavity

Objective To study the outcome of lost gallstones in peritoneal cavity. Methods Gallstones and bile collected from 51 patients undergoing laparoscopic cholecystectomy were analysed and cultured.One to three gallstones from each patient were placed into the peritoneal cavity of a corresponding Wistar rat on sterile condition. Results 8 rats died of peritoneal infection, intestinal fistula and ileus within one month. Abdominal wall abscess occured to one rat. All survival rats were sacrificed three months later. Pathologic results showed that the nidus of abscess appeared in tissue around the stone. Conclusions Lost gallstone is harmful to body. We should avoid gallstone lost in peritoneal cavity.