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骨肉瘤患者延长生命保存肢体的临床研究(136例15年回顾)
引用本文:姚长海,侯树勋,刘汝落,周天健,赵海龙.骨肉瘤患者延长生命保存肢体的临床研究(136例15年回顾)[J].中国矫形外科杂志,1997(5).
作者姓名:姚长海  侯树勋  刘汝落  周天健  赵海龙
作者单位:解放军第304医院全军骨科中心,北京博爱医院,白求恩医大一院
摘    要:作者1981~1996年共治疗骨肉瘤患者136例,随访5~15年。2年生存率61%,5年生存率26.5%。作者首次在国内将大剂量顺铂全身化疗、双途径化疗以及DSA介入化疗用于骨肉瘤术前化疗。在136例骨肉瘤患者中保肢手术80例,其中开创放疗是国内首次开展。作者还对骨肉瘤的早期诊断、术前化疗、保肢手术以及肺转移瘤切除等问题提出了自己的看法。

关 键 词:骨肉瘤  外科分期系统  双途径化疗

Life survival and Limb salvage Operation for Osteosarcoma:A Fifteen year Clinical Study in 136 Patients
Yao Changhai,Hou Shuxun,Liu Ruluo,et al..Life survival and Limb salvage Operation for Osteosarcoma:A Fifteen year Clinical Study in 136 Patients[J].The Orthopedic Journal of China,1997(5).
Authors:Yao Changhai  Hou Shuxun  Liu Ruluo  
Institution:Yao Changhai,Hou Shuxun,Liu Ruluo,et al.Orthopedic Center of PLA,No.304 Hospital PLA,Beijing 100037.
Abstract:From 1981 to 1986,authors treated 136 patients with osteosarcoma.The follow up time ranged from 5 to 15 years.The 2 year survival rate reached 61%and 5 year survival rate was 26 5%.It was first in this country that the authors applied high dose cisplatin systemic chemotherapy,two route chemotherapy,catheterized chemotherapy by DSA for preoperative treatment of osteosarcoma,and limb salvage surgery combined with the intraoperative radiotherapy in 80 patients.The early diagnosis,preoperative chemotherapy,limb salvage surgery and excision of metastatic lesion of lungs were discussed in the paper.
Keywords:Osteosarcoma  Enneking surgical staging system  Two  route chemotherapy  
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