| 艾塞那肽治疗口服药失效血糖控制不佳的肥胖型2型糖尿病患者的疗效和安全性 |
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| 引用本文： | 龚叶,姚翡,郁秋荣.艾塞那肽治疗口服药失效血糖控制不佳的肥胖型2型糖尿病患者的疗效和安全性[J].实用药物与临床,2013,16(6):547-548. |
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| 作者姓名： | 龚叶 姚翡 郁秋荣 |
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| 作者单位： | 常熟市第二人民医院内分泌科,江苏常熟,215500 |
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| 摘 要： | 目的观察艾塞那肽联合二甲双胍和磺脲类药物治疗口服药失效血糖控制不佳的肥胖型2型糖尿病患者的疗效和安全性。方法在用二甲双胍+磺脲类药物治疗血糖控制欠佳的肥胖型2型糖尿病患者加用艾塞那肽治疗6个月后,观察其FPG、PPG、HbA1c、低血糖发生率、体重变化情况。结果与治疗前相比,患者的FPG、PPG、HbA1c、体重变化均显著下降(P<0.05)。结论艾塞那肽可以显著改善患者的血糖,降低HbA1c,使血糖达标,同时还可以持续降低体重。
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| 关 键 词： | 艾塞那肽 2型糖尿病 肥胖 |
Efficacy and safety of exenatide on type 2 diabetes obesity patients with blood control failure |
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| GONG Ye
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YAO Fei
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YU Qiu-rong.Efficacy and safety of exenatide on type 2 diabetes obesity patients with blood control failure[J].Practical Pharmacy and Clinical Remedies,2013,16(6):547-548. |
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| Authors: | GONG Ye YAO Fei YU Qiu-rong |
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| Institution: | (Department of Endocrinology,The Second People’s Hospital of Changshu City,Changshu 215500,China) |
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| Abstract: | Objective To observe the efficacy and safety of exenatide on type 2 diabetes patients with blood control failure.Methods Type 2 diabetes obesity patients w ith metformin plug sulfonylureas treatment failure were given exenatide for 6 months and FPG,PPG,HbA1c,incidence of low blood,w eight changes of the patients were observed.Results Compared w ith before treatment,patients' FPG,PPG,HbA1c,incidence of low blood sugar,w eight changes all significantly decreased(P < 0.05).Conclusion Exenatide can significantly improve patients' blood sugar,reduce blood sugar HbA1c,and at the same time also can steadily reduce weight. |
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| Keywords: | Exenatide Type 2 diabetes Obesity |
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