胰岛素联合口服药二甲双胍治疗2型糖尿病的临床体会

目的：探讨胰岛素联合口服药二甲双胍治疗2型糖尿病的临床效果。方法选取我院于2011年10月～2012年10月收治的2型糖尿病患者60例，随机分为观察组与对照组，各30例。对照组仅给予二甲双胍口服治疗，观察组给予胰岛素联合二甲双胍实施治疗，观察两组的治疗效果。结果治疗后，两组的血糖水平较治疗前均明显下降，且观察组的血糖水平明显优于对照组，P＜0.05；观察组的总有效率明显高于对照组（96.67% VS 70.00%），不良反应发生率明显低于对照组（26.67% VS 73.33%），差异有统计学意义（P＜0.05）。结论胰岛素联合口服药二甲双胍治疗2型糖尿病，疗效显著，不良反应少，值得临床推广。

Clinical efficacy of insulin combined with oral metformin in treatment of type 2 diabetes

Objective To discuss clinical efficacy of insulin combined with oral metformin in treatment of type 2 diabetes.MethodsSelected 60 cases with type 2 diabetes from October 2011 to October 2012 admitted in our hospital were randomly divided into observation group and control groups, each group with 30 cases. Control group were given oral medication metformin, and observation group was treated with insulin combined with oral metformin. The clinical efficacy was observed in two groups. Results After treatment, blood glucose levels in two groups decreased significantly more than before treatment, and glucose level in the observation group was lower than the control group,P〈0.05; The total efficiency of the observation group was significantly higher than control group（96.67% VS 70.00%）, and incidence of adverse reactions was significantly lower than control group （26.67% VS 73.33%）,P〈0.05,with statistically significant difference.ConclusionInsulin combined with oral metformin in treatment of type 2 diabetes shows significant effect, less adverse reactions, worthy of clinical promotion.