慢性阻塞性肺疾病急性发作合并2型糖尿病患者使用糖皮质激素后血糖变化的观察

目的：观察慢性阻塞性肺疾病急性发作（AECOPD）合并2型糖尿病（T2DM）患者在治疗过程中使用糖皮质激素后其血糖变化情况与胰岛素用量的关系。方法搜集我院住院患者中AECOPD且合并T2DM患者病例50例，入院时立即查血糖，并评估病情了解其是否需要使用糖皮质激素，及使用胰岛素的情况。使用糖皮质激素后开始监测空腹、餐后和（或）随机血糖，记录胰岛素调整剂量。采用SPSS13.0统计软件统计，（x ± s），Z检验,计算P值。结果使用糖皮质激素后AECOPD合并T2DM患者的各时段血糖数值有升高，差异均无统计学意义（P＞0.05），日均胰岛素使用量增加明显，差异有统计学意义（P=0.0092）。结论AECOPD合并T2DM患者使用糖皮质激素安全，可控。

The observation of blood sugar changes after using glucocorticoid on patients with acute exacerbation chronic obstructive of pulmonary disease and type 2 diabetes

Objective To observe the changes of blood glucose on patients with acute exacerbation chronic obstructive of pulmonary disease and type 2 diabetes after using corticosteroids in the treatment process and the relationship to the insulin dosage. Methods 50 cases of patients in our hospital with T2DM and AECOPD were collected, and they were checked blood sugar immediately after admission, and the condition about whether they need the use of corticosteroids and the use of insulin were assessed. After the use of glucocorticoids,the fasting,postprandial and / or random blood glucose were monitored , insulin dose adjustment was record. Using statistical software SPSS13.0 ,（x ± s）,Z test, P value was calculated. Results Each period of blood glucose in patients with AECOPD and T2DM values were elevated after the use of glucocorticoids, P〉0.05, the difference was not statistically significant, the average daily insulin usage increased significantly, P=0.0092, the difference had statistical significance. Conclusion The glucocorticoid use in patients with AECOPD and T2DM is safety, controllable.