术前选择性经肝动脉化疗栓塞对肝癌患者手术治疗效果的影响

目的：探讨术前经肝动脉化疗栓塞术（TACE）对肝细胞肝癌（HCC）肝切除患者生存及预后的影响。方法回顾性分析130例肝癌患者资料，术前选择性经肝动脉化疗栓塞（TACE组）65例，术前未行经肝动脉化疗栓塞（对照组）65例。比较术后1、2、3年复发率及生存率变化，评价可切除肝癌术前选择性经肝动脉化疗栓塞的作用。结果1、3年复发率两组无差异，2年复发率TACE组为31.2%，对照组为59.2%，TACE组明显低于对照组（P＜0.05）；3年生存率TACE组为54.1%，对照组为32.3%，TACE组明显高于对照组（P＜0.05）。结论可切除肝癌术前严格掌握条件选择性TACE可在一定程度上提高手术治疗的效果。

Effect of preoperativeelective transc atheterarterial chemoembolization on surgical effect of patients with hepatic carcinoma

Objective To explore the effect of preoperative transcatheter arterial chemoembolization（TACE） on life quality and prognosis of patients with hepatocellular carcinoma receiving hepatectomy. Methods Data of 130 patients with hepatic cancer were analyzed retrospectively. 65 patients received preoperative TACE（TACE group）, and 65 patients did not receive preoperative TACE（control group）. Changes of relapse rate and survival rate in 1, 2, 3 years after the surgery were compared, and the effect of preoperative TACE for resectable hepatic cancer was evaluated. Results There was no difference of 1-year and 3-year relapse rate between the two groups. 2-year relapse rate in the TACE group was 31.2%, significantly lower than that of 59.2%in the control group（P〈0.05）;3-year survival rate in the TACE group was 54.1%, significantly higher than that of 32.3%in the control group（P〈0.05）. Conclusion Preoperative elective TACE for resectable hepatic cancer under strict conditions, to some extent, can improve the curative effect of the surgery.