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精神心理因素对肺癌发病影响的研究
引用本文:宋欢,蒋婷婷,严丽波,彭夏莹,余敏,刘煜,卢铀. 精神心理因素对肺癌发病影响的研究[J]. 现代预防医学, 2011, 38(2): 294-297
作者姓名:宋欢  蒋婷婷  严丽波  彭夏莹  余敏  刘煜  卢铀
作者单位:1. 四川大学华西医院胸部肿瘤科,成都,610041
2. 四川大学华西临床医学院
摘    要:[目的]探讨四川地区原发性肺癌的独立危险因素,重点分析精神心理因素对肺癌发病的影响程度。[方法]纳入原发性肺癌患者404名,按性别相同、年龄±2岁1︰2匹配选取健康人群808例。对所有参与者进行问卷调查后建立数据库,采用单因素和多因素Logistic回归进行分析。[结果]单因素分析发现24个暴露因素与肺癌发病有关;多因素分析显示主动及被动吸烟史、血缘亲属肿瘤家族史、住宅3km内有大型排污工厂、10年内有搬入新近(﹤3月)装修房屋居住史及精神心理因素,包括工作强度很大(OR=4.76,95%CI:2.24~10.10)、较大(OR=5.39,95%CI:3.05~9.54)、有一定强度(OR=3.74,95%CI:2.09~6.74)、睡眠质量差(OR=2.17,95%CI:1.47~3.24)、性格急躁(OR=2.05,95%CI:1.47~2.85)、缺乏解压途径(OR=1.90,95%CI:1.36~2.67)为主要独立危险因素。[结论]四川地区肺癌的发生与多种暴露因素有关。对现代肺癌人群来说,精神心理因素已成为了不可忽视的致病原因之一。

关 键 词:肺肿瘤/流行病学  病例-对照研究  精神心理因素  危险因素

CASE-CONTROL STUDY ON THE RISK FACTORS OF LUNG CANCERS IN SICHUAN
SONG Huan,JIANG Ting-ting,YAN Li-bo,et al.. CASE-CONTROL STUDY ON THE RISK FACTORS OF LUNG CANCERS IN SICHUAN[J]. Modern Preventive Medicine, 2011, 38(2): 294-297
Authors:SONG Huan  JIANG Ting-ting  YAN Li-bo  et al.
Affiliation:SONG Huan,JIANG Ting-ting,YAN Li-bo,et al.(Department of Thoracic Cancer,Cancer Center,West China Hospital,Chengdu 610041,China)
Abstract:[Objective]To investigate main risk factors of primary lung cancers in Sichuan,particularly focus on the psychological factors.[Methods]We enrolled 404 patients,who were newly-diagnosed definitely as primary lung cancer at West China Hospital of Sichuan University from March to November 2009,and 808 health population were matched by age and sex.Information on various aspects,including psychological factors,was gathered through personal interviews by structured questionnaire.The data were pooled into univari...
Keywords:Lung neoplasm/epidemiology  Case-control studies  Psychological factor  Risk factors  
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