Infantile Osteomyelitis Secondary to Malignant Osteopetrosis |
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Authors: | Sunita Managutti Anil Managutti Michael Pragasm |
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Institution: | (1) Department of Oral and Maxillofacial Pathology, Modern Dental College and Research Centre, Indore, 453112, Madhya Pradesh, India;(2) Department of Oral and Maxillofacial Surgery, Modern Dental College and Research Centre, Indore, 453112, Madhya Pradesh, India; |
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Abstract: | Osteopetrosis (OP) is a rare congenital disorder (present at birth) in which the bones become over dense. This results from
an imbalance between the formation of bone and the resorption of the bone. Thickening of the bones which become abnormally
dense due to an inherited defect in bone resorption, the process in which old bone is broken down and removed so that new
bone can be added to the skeleton. Osteoclasts are the cells responsible for bone resorption. In osteopetrosis the osteoclasts
do not perform normally. This flaw in bone resorption results in bones that are abnormally dense, yet are fragile and easily
broken. Osteopetrosis is also known as Albers–Schonberg disease, generalized congenital osteosclerosis, ivory bones, marble
bones, osteosclerosis fragilis generalisata. In this article, we have described about the diagnosis and medical and surgical
management of osteopetrosis reported case to our hospital. |
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Keywords: | Osteomyelitis Osteopetrosis Marble bone disease |
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