The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment |
| |
| Authors: | Nasreddine Ziad S Phillips Natalie A Bédirian Valérie Charbonneau Simon Whitehead Victor Collin Isabelle Cummings Jeffrey L Chertkow Howard |
| |
| Affiliation: | From the*Center for Clinical Research, Neurology Service, H?pital Charles LeMoyne, Quebec, Canada?Memory Clinic Neuro Rive‐Sud, Université de Sherbrooke, Quebec, Canada?Bloomfield Center for Research in Aging, Lady Davis Institute, and §Department of Clinical Neurosciences and Division of Geriatric Medicine, Sir Mortimer B. Davis—Jewish General Hospital, McGill University and Division of Geriatric Medicine, Montreal, Quebec, Canada∥Research Center, University Institute of Geriatrics, University of Montreal, Montreal, Quebec, Canada?Center for Research in Human Development/Department of Psychology, Concordia University, Montreal, Quebec, Canada#Department of Psychology, University of Quebec at Montreal, Montreal, Quebec, CanadaDepartments of**Neurology??Psychiatry and Biobehavioral Sciences, David Gellen School of Medicine, University of California at Los Angeles, Los Angeles, California. |
| |
| Abstract: | ![]()
OBJECTIVES: To develop a 10-minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first-line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia. DESIGN: Validation study. SETTING: A community clinic and an academic center. PARTICIPANTS: Ninety-four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini-Mental State Examination (MMSE) score > or =17), and 90 healthy elderly controls (NC). MEASUREMENTS: The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD. RESULTS: Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively). CONCLUSION: MCI as an entity is evolving and somewhat controversial. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE. |
| |
| Keywords: | MoCA mild cognitive impairment Alzheimer's cognitive assessment |
| 本文献已被 PubMed 等数据库收录！ |
|
