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An Animal Model for the Study of the Function of Pregnancy-Specific Beta1 Glycoprotein and Pregnancy Zone Protein: A Review* |
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| Authors: | J. HAU P. SVENDSEN J. CHEMNITZ B. TEISNER J.G. WESTERGAARD |
| Abstract: | ABSTRACT: Two pregnancy-associated murine proteins, PAMP-1 and PAMP-2, have been found to be immunologically cross-reacting analogues to the human proteins pregnancy zone protein (PZP) and pregnancy-specific beta1-glycoprotien (SP-1), respectively. In this study, the physiochemical and biological properties of the proteins are compared and the effect on pregnancy of administration of monospecific antibodies against the proteins is reported. |
| Keywords: | Pregnancy zone protein pregnancy-specific beta1-glycoprotein pregnancy-associated murine protein immunological cross-reaction corticosteroid-binding globulin liver parenchymal cells trophoblastic cells abortion |