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Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity |
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| Authors: | Mette Levinsen Susanne Rosthøj Ulrikka Nygaard Jesper Heldrup Arja Harila-Saari Olafur G. Jonsson Anne Grete Bechensteen Jonas Abrahamsson Birgitte Lausen Thomas L. Frandsen Richard M. Weinshilboum Kjeld Schmiegelow |
| Affiliation: | 1. Department of Paediatrics and Adolescent Medicine, The University Hospital Rigshospitalet, Copenhagen, Denmark 2. Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark 3. Department of Pediatrics, Sk?ne University Hospital, Lund, Sweden 4. Department of Pediatrics, University Hospital, Oulu, Finland 5. Department of Pediatrics, Landspitali, Reykjavík, Iceland 6. Department of Pediatrics, Oslo University Hospital, Oslo, Norway 7. Department of Pediatrics, Queen Sylvias Children Hospital, Gothenburg, Sweden 8. Department of Molecular Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology, Mayo Clinic, Rochester, MN, USA 9. Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark |
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